Benzocaine- local anesthetic commonly used as a topical pain reliever or in cough drops.

Benzocaine- local anesthetic commonly used as a topical pain reliever or in cough drops.

Benzocaine; Ethyl 4-aminobenzoate; Ethyl p-aminobenzoate, Ethyl aminobenzoate.

Benzonac, Biomycetin, Buz, Ceruklin, Chloromycetin DPS, Clearwax, Desol, Despol, Drep wax, Enteromycetin Otic, Ezwax, Fastwax, Healex Plus Spray, Healex Spy, Mandelay, Megacid-B, Mamdew Baby Gel, Mucopain, Nill-O-Wax, Naya

ethyl 4-aminobenzoate

It binds to Na channels and stabilizes the neuronal membrane reversibly which decreases its permeability to sodium ions. Depolarization of the neuronal membrane is inhibited thereby blocking the initiation and conduction of nerve impulses.

Apply as directed by physician.

Benzocaine is a local anesthetic commonly used as a topical pain reliever.

Hypersensitivity reactions; nystagmus; vertigo; sensitization.  CNS excitation; blurred vision; nausea and vomiting; drowsiness. muscle twitching and tremors; convulsions. Numbness of tongue; CVS effects.

Antagonism with sulfonamides; aminosalicylic acid; anticholinesterases; suxamethonium; antiarrhythmics; MAOIs; TCAs.

• Hypersensitivity.
• Complete heart block. Low plasma-cholinesterase concentrations.
•  Pyrogenic infection at or near the skin.
• Injection into or application to inflamed, to damaged skin mucosa, infected tissues, or on perforated tympanic membrane.

Store it at controlled room temperature.

Molecular weight

165.1891

Molecular formula

C9H11NO2

CAS number

94-09-7

Precautions

·       Elderly, debilitated, child.

·       Avoid contact with middle ear; prolonged use or application on extensive areas of the skin.

·       Epilepsy impaired cardiac conduction or respiratory function, shock or hepatic impairment.

·       Avoid eating or drinking for at least 3-4 hr after the anaesthetic; rubbing or touching the eye while anaesthesia persists.

·       Myasthenia gravis.

·       The anaesthetised eye should be protected from dust and bacterial contamination. Chemical burns must be neutralised before treatment with benzocaine. Pregnancy.