Fatty acids from fish beneficial to prevent Alzheimer’s

• The research published in the FASEB Journal suggested that Omega-3 polyunsaturated fatty acids (PUFAs) found in fish oil could improve the function of the glymphatic system, which facilitates the clearance of waste from the brain.
• To make this discovery, scientists first used transgenic fat-1 mice, which express high endogenous Omega-3 PUFAs in the brain, to investigate the effect of Omega-3 PUFAs on the clearance function of the glymphatic system.
• Compared to the wild-type mice, the fat-1 mice with enriched endogenous Omega-3 PUFAs significantly promote the clearance function of the lymphatic system, including the amyloid-beta clearance from the brain.
• Wild-type mice were supplemented with fish oil, which contains high concentrations of Omega-3 PUFAs, and found that fish oil-supplemented mice also improved the clearance function of the glymphatic system compared to the control mice without fish oil supplementation.
• Omega-3 PUFAs help maintain the brain homeostasis, which may provide benefits in a number of neurological diseases, such as Alzheimer’s disease, traumatic brain injury, and sleep impairment, among others.
• “The brain is an extremely vascularised organ, while we might also bear in mind that Omega-3 fatty acids may impact neurons, glia, and astrocytes themselves,” 

Fatty acids from fish, beneficial, alzheimers