In the present study we report the antimicrobial and antioxidant activities of leaf extracts of Sophora interrupta. Different solvent extracts were prepared using methanol, acetone and hexane. Methanolic extract of S. interrupta (MES) showed effective antimicrobial activity against both bacterial and fungal pathogens compared with acetone extract of S. interrupta (AES) and hexane extract of S. interrupta (HES). MES formed maximum inhibition zone against bacteria B. subtilis (8.2 mm) and fungus Candida albicans (7.3 mm). AES showed maximum inhibition zone against bacteria S. aureus (6.8 mm) and fungus Aspergillus niger (6.4 mm). HES displayed maximum inhibition zones of 4.3 and 4.6 mm against bacteria B. subtilis and fungus C. albicans. Both MES and AES also showed effective antioxidant activity by showing radical scavenging activity against DPPH and H2O2 free radicals. Fourier transform infra red (FTIR) spectrum analysis revealed that the secondary metabolites present in the extract such as terpenoids, saponins, flavonoids, polyphenolics and proteins were responsible for the bioactivities of S. interrupta.
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