Among several respiratory diseases affecting man, bronchial asthma is the most common disabling syndrome. The therapy of asthma usually employs steroids or disease modifying drugs. The long-term use of these, however, may not limit the disease progression. All of these drugs have side effects and the search for a novel anti-asthmatic drug continues. There is a dire need to identify effective and safe remedies to treat bronchial asthma. The present study deals with the effect of methanolic extract of leaves by using animal model. This study is based on the effect of Calotropis procera leaves extract on chlorine induced asthma in Albino mice. The study shows that extract is effective against chlorine induced asthma. CPME at 250 mg/kg showed a significant affect against Cl2 induced asthma when compared to all other groups
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