To describe a standard operating procedure (SOP) for performing pressure filtration.
1.0 PURPOSE:
To describe a standard operating procedure (SOP) for performing pressure filtration.
2.0 SCOPE:
The SOP describes in detail the method of pressure filtration.
3.0 RESPONSIBILITY:
The responsibility of carrying out pressure filtration as per the SOP lies with the staff of the rank not lower than operator of the production department.
The responsibility of preparing, reviewing and approving the SOP lies with the Officer (Production), Head of Production and Head of QAD respectively.
4.0 METHOD:
4.1 Connect the pressure filter to reactor bottom valve.
4. 2 Open the bottom valve. When pressure filter is full, the filtrate enters to SS chariot. Arrange candle filter. Connect the hose pipe to candle filter inlet and the other end of the hose pipe is put in SS Chariot. Connect the candle filter outlet to another reactor charging line.
4. 3 Open the valve connecting to another reactor which is connected to vacuum.
4. 4 The filtration can be carried out by using nitrogen pressure (5 - 7PSI).
4.5 After completion of filtration wash pressure filter with industrial methylated spirit and collect the washings also into the reactor.
5.0 RECORDING:
The pressure filtration operation will be recorded by the staff of rank not lower than
operator in the batch manufacturing sheet.
Pressure filtration, production
