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Nadifloxacin

It is a topical fluoroquinolone antibiotic for the treatment of acne vulgaris. More

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Description

It is a topical fluoroquinolone antibiotic for the treatment of acne vulgaris.

Generic Name

Nadifloxacin

Chemical names

Nadifloxacin; 124858-35-1; Jinofloxacin; Nadixa; OPC-7251

Brand names

NA

IUPAC name

7-fluoro-8-(4-hydroxypiperidin-1-yl)-12-methyl-4-oxo-1-azatricyclo[7.3.1.0?,¹³]trideca-2,5,7,9(13)-tetraene-3-carboxylic acid

Pharmacokinetics

NA

Actions

Nadifloxacin inhibits the bacterial enzyme DNA gyrase. The enzyme is important for the bacterial replication process.

Dosage/Dosage form

Apply a thin layer of Nadifloxacin cream onto the affected area.

Therapeutic uses

Nadifloxacin is a topical antibiotic indicated for the treatment of acne vulgaris.

Adverse effects/Side effects

Increased sweating, irritation, itching, redness, papules, flushes, feeling of warmth, contact dermatitis and dryness of the skin.

Interaction

NA

Contraindications

Nadifloxacin is contraindicated in patients who are allergic to fluoroquinolones and its derivatives.

Storage

Store in a cool and dry place.

Information

Molecular weight

360.385

Molecular formula

C19H21FN2O4

CAS number

124858-35-1

Precautions

Nadifloxacin should be used only for topical use.