Scopolamine

Scopolamine

NSC61806; (-)-Scopalamine HBr

Transderm-scop, transderm-V, isopto hyoscine, scopace.

(1R,2R,4S,5S,7R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0²,?]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate

Absorption: 10-50%, excreted through urine

Scopolamine acts by interfering with the transmission of nerve impulses by acetylcholine in the parasympathetic nervous system (specifically the vomiting center).

            Scopolamine is a muscarinic antagonist structurally similar to the neurotransmitter acetylcholine and acts by blocking the muscarinic acetylcholine receptors and is thus classified as an anticholinergic.

• Scopolamine hydrochloride injections-0.4,0.6 mg/ml, IM, IV, SC
• Transderm-scop patch

Preanesthesia, nausea, vomiting, motion sickness, pupilary dilation, parkinsonian tremor.

: Blurred vision, chest pain, mood change, sweating, irregular heartbeat, shortness of breath.

• The severity or risk of adverse effects can be increased when scopolamine is combined with 1,1,1,2 tetra fluoroethane, 7-Nitroindazole, Acepromazine.
• The serum concentrations of Acetaminophen, Acetyl salicylic acid can be increased when it is combined with scopolamine.

Contraindicated in a patients of prostatic hypertrophy, angle closure glaucoma and renal impairment.

Store scopolamine at room temperature

Molecular weight

303.3529

Molecular formula

C17H21NO4

CAS number

51-34-3

Precautions

This medicine may cause drowsiness, trouble with thinking, or trouble with seeing clearly.