Natamycin

Natamycin, also known as pimaricin, is an antifungal medication used to treat fungal infections around the eye.

Natamycin

NATAMYCIN; Pimaricin; 7681-93-8; Tennecetin; Myprozine

Elmycin, Natacin, Natadrops, Natam, Natamet, Natoptic, Pimafusin, Pimafusin Vaginal

(1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-22-{[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.0?,?]octacosa-8,14,16,18,20-pentaene-

NA

It is a tetraene polyene antibiotic derived from Streptomyces natalensis. It possesses activity against a variety of filamentous fungi and yeast including Candida, Cephalosporium, Aspergillus,  Fusarium and Penicillium in vitro.

Instill 1 drop 1-2 hourly (As 5% solution) Ophthalmic

For the treatment of fungal blepharitis, conjunctivitis, and keratitis caused by susceptible organisms including Fusarium solani keratitis.

GI disturbances (oral). Irritation (local). Conjunctival chemosis and hyperaemia (ophthalmic).

• When used in combination with Amlodipine the therapeutic efficacy of Natamycin can be increased.
• The therapeutic efficacy of Natamycin can be increased when used in combination with Amrinone.
• The therapeutic efficacy of Natamycin can be increased when used in combination with Barnidipine.

Hypersensitivity

Store in a cool place.

Molecular weight

665.733

Molecular formula

C33H47NO13

CAS number

7681-93-8

Precautions

Avoid long-term use of this medication.