Aceclofenac

Aceclofenac

Aceclofar, Aceclofenac, Falcol, Preservex, Gerbin

A-Niclo, Abate SR, Acewalk, ACB, Aceact injection, Acota FC 100 mg, Acota, Hifenac, Movon SR, Nano, Zerodol, Zerodol.

2-[(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid

It is a non-steroidal anti inflammatory agent. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase; cyclooxygenase converts arachidonic acid to cyclic endoperoxides, it is the precursors of prostaglandins. Prostaglandin synthesis inhibition accounts for their antipyretic, analgesic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. 

• A-Niclo 100 mg
• Abate SR 200 mg
• ACB 100mg
• Aceact injection 150mg/1 ml
• Acewalk 100mg mouth dissolving tablet
• Acewalk 200mg sustained release tablets
• Acota FC 100 mg
• Acota 100mg film coated tablet
• Hifenac (tablets, injections, gel)
• Movon SR 200mg capsule
• Nano 150 mg /1 mL injection
• Zerodol 200 mg controlled release tablet
• Zerodol 100mg film coated tablet.

• Analgesic
• Antipyretic
• Platelet-inhibitory actions
• Rheumatoid arthritis,
• Osteoarthritis
• Ankylosing spondylitis.

Nausea, abdominal pain, blood dyscrasias, rashes, nephrotoxicity, GI bleeding.

• The risk or severity of adverse effects can be increased when Aceclofenac is combined with the following drugs.

• 16-Bromoepiandrosterone
• 19-norandrostenedione
• 4-Androstenedione
• 5-androstenedione
• Acetovanillone

• Aceclofenac may increase the anticoagulant activity of Acenocoumarol, Abciximab.
• The metabolism of aceclofenac can be decreased when combined with Abiraterone.

Pregnancy and lactation, Hypersensitivity to aspirin or NSAIDs, history of peptic ulceration or GI bleed, moderate to severe renal impairment.

Protect from light. Store in an air tight container in a cool and dry place.

Molecular weight

354.18

Molecular formula

C16H13Cl2NO4

CAS number

89796-99-6

Precautions

Cautiously administer to patients with ulceratove colitis, GI diease, Crohn`s disease, hepatic porphyria, haematological abnormalities, history of bronchial asthama, heart failure or hypertension; mild renal, cardiac or hepatic impairment.