Acetylcysteine

It help to thin and loosen mucus in the airways due to lung diseases such as emphysema, bronchitis etc

Acetylcysteine

Acetylcysteine, N-Acetyl-L-cysteine, N-Acetylcysteine, Acetadote, N-Acetyl-cysteine.

Cilol, Evanac, Fluimucil, Flumucil, Fourts-B, Gluton-600, Koxcure, Mucomelt-A, Mucomix, Mucyst Ampoule, Mucyst Inj, Nefrosave Forte, Ovacare Forte, Vensy.

(2R)-2-acetamido-3-sulfanylpropanoic acid

• Absorption: Oral and topical
• Distribution: 83% protein binding
• Metabolism: Hepatic
• Excretion: Urine

It is most effective when given early, with benefit seen principally in patients treated within 8-10 hours of the overdose. Acetylcysteine has been shown to reduce the extent of liver injury following acetaminophen overdose. Acetylcysteine likely protects the liver by maintaining or restoring the glutathione levels, or by acting as an alternate substrate for conjugation with, and thus detoxification of, the reactive metabolite.

• Inhalant oral 100 mg/mL, 200 mg/mL
• Injection IV 200 mg/mL
• Solution oral and IV 200 mg

• Mucolytic agent
• Management of acetaminophen poisoning.
• General antioxidant 
•  Ischemic brain injury
• N-acetylcysteine is now widely used in the treatment of HIV

Flushing, stomatitis, fever, nausea, rhinorrhoea, vomiting, bronchospasm, bradycardia, blurred vision, anaphylactoid reactions, syncope, thrombocytopenia, convulsions.

Potentially Fatal: Rarely, respiratory or cardiac arrest.

During pregnancy and in breast feeding women’s.

Store between 59-86°F (15-30°C). 

Molecular weight

163.195

Molecular formula

C5H9NO3S

CAS number

616-91-1

Precautions

Asthmatic patients, history of bronchospasm, peptic ulceration, Pregnancy.