Adapalene

It is a topical retinoid used in the treatment of acne

Adapalene

Differin, Adaferin, 6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoic acid.

Aclene, Acneris-AD, Acnovate, Adapen, Adaple gel, Adaple-C, Alene GEL, Baclytic, Clinderm-A, Clindex, Clinpic-A, Clinred-A, Deriva-C, Difra Gel, Edplin, Edplin-C, Euclin-A, Faceclin-A.

6-[3-(adamantan-1-yl)-4-methoxyphenyl]naphthalene-2-carboxylic acid

• Absorption: Topical
• Excretion: Bile

It is a stable retinoid. Basing on the pharmacological and biochemical profile adapalene is demonstrated a modulator of keratinization, inflammatory processes and cellular differentiation, all of which represent important features of acne vulgaris pathology.

Topical application: After washing the skin a thin film of gel should be applied on the affected area once the day.

Acne, prevention of pimples

Mild skin irritation, erythema, redness of skin, scaling, and sensations of stinging, cutaneous dryness, itching, burning and pruritus.

• Products contain astringents and alcohol
• Increased irritation may occur with medicated or abrasive soaps

Hypersensitivity

Store away from excess heat and moisture, store at room temperature.

Molecular weight

412.5201

Molecular formula

C28H28O3

CAS number

106685-40-9

Precautions

• Avoid exposure to sunlight
• Avoid applying cosmetics
• Avoid contact with mouth
• Caution should be exercised in patients with allergy, eczema, sunburn, during pregnancy and lactation and the person who are taking other medications.