Alendronic acid or alendronate sodium is a bisphosphonate drug used for osteoporosis, osteogenesis imperfecta, and several other bone diseases. More
Alendronic acid or alendronate sodium is a bisphosphonate drug used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.
Alendronic acid
Alendronate, Alendronic acid, Fosamax, Arendal, Alendronate sodium
Ados, Denfos, Alenost, Alenost-D, Bifosa. Cufosa, Dronal, Fosavance. Osteofos, Ostonat, Poronil, Ralenost-10, Restofos, T-Score Kit, Zophost
(4-amino-1-hydroxy-1-phosphonobutyl) phosphonic acid
Absorption: IV
Distribution: 78% protein binding
Excretion: Urine
Alendronate, a second-generation bisphosphonate is the first member of a group of drugs which strengthens bone. It is used to treat corticosteroid-induced osteoporosis and Paget's disease, to reduce hypercalcemia in tumor-induced bone disease, and to prevent osteoporosis in postmenopausal women.
The recommended dose per day is 5-10 mg or 35-70 mg once in a week.
Used in the treatment of osteoporosis in men, postmenopausal women and for Pagets disease.
Oesophagitis, constipation, oesophageal ulcers, & erosions, dysphagia, heartburn, retrosternal pain, abdominal pain, distension, flatulance, diarrhoea, headcahe, erthyema, rash, musculoskeletal pain, transient decreases in serum phospate.
Highly active vitamin D analogues or fluorides
Contraindicated in lactation and pregnancy.
Store it at room temperature in a well closed container.
249.096
C4H13NO7P2
66376-36-1
History of ulcers, Upper Gi disorders (discontinue if symptoms worsen), active GI bleeding. Correct Vitamin D & Ca deficiency before starting therapy.
