Amlexanox is an anti-inflammatory antiallergic immunomodulator used to treat recurrent aphthous ulcers, and several inflammatory conditions.
Amlexanox
Amlexanox, Amoxanox, Aphthasol, Solfa
Amlenox, Lexanox
2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno [2, 3-b] pyridine-3-carboxylic acid
As a benzopyrano-bipyridine carboxylic acid derivative, amlexanox has anti-inflammatory and antiallergic properties. Amlexanox inhibits chemical mediatory release of the SRS-A (slow-reacting substance of anaphylaxis) and may have antagonistic effects on interleukin-3. When cells are under stress, they release an inactive form of human FGF-1 (fibroblast growth factor1), a potent mitogen. Amlexanox binds to FGF1, increasing its conformational stability, sterically blocking Cu (2+) induced oxidation which normally leads to activation of FGF-1.
Apply ¼ inch or 0.5 cm 4 times a day, onto the ulcers with clean/sterile fingertip until healing of oral cankers.
Aphthous ulcers or canker sores of the mouth.
Mucositis, stinging, slight pain, burning, nausea and diarrhea.
Hypersensitivity
Store at 20-25°C.
298.2934
C16H14N2O4
68302-57-8
Do not take Amlexanox, if you have immune system disorders or if you are on cancer treatment. Avoid excess dosage.
