Amoxicillin is an antibiotic useful for the treatment of a number of bacterial infections. It is the first line treatment for middle ear infections. More
Amoxicillin is an antibiotic useful for the treatment of a number of bacterial infections. It is the first line treatment for middle ear infections.
Amoxicillin
Amoxicillin, Amoxycillin, Amoxicillin anhydrous, Amoxicilline, Clamoxyl
Abclox, Abimox-DC, Amoxinga SYR, ACL, Allmox SYR, Aclowell-L, Alexi-DX, Acmox, Acmox TAB, Acmox-DS, Actimox, Adcil, Alnaclox, Adclox-D, Afymox-DT, Afymox-DX, Agmox, Amolac 250, Agmox-DX, Agmox-LB, Alclox-D, Aldico, Allmox,
(2S,5R,6R)-6-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
It is a moderate-spectrum antibiotic effective against a wide range of Gram+ve, and a limited range of Gram-negative organisms. Amoxicillin binds to PBP-1A (penicillin-binding protein 1A) located inside the bacterial cell well. Penicillin-sensitive transpeptidase the penicillin’s acylate C-terminal domain by opening the lactam ring. This inactivation of the enzyme prevents the formation of a cross-link of two linear peptidoglycan strands, inhibiting the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that amoxicllin interferes with an autolysin inhibitor.
Used to treat bacterial infections caused by microorganisms.
Hyperactivity, agitation, dizziness, insomnia, maculopapular rash, urticaria, exfoliative dermatitis, hypersensitivity vasculitis; diarrhoea, nausea, vomiting; anaemia, thrombocytopenia, leucopenia, and agranulocytosis.
Caution when used during pregnancy, Hypersensitivity and lactation.
Store at 20-25°C.
365.404
C16H19N3O5S
26787-78-0
Renal and hepatic disease, lactation, pregnancy, infectious mononucleosis.
