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Antithrombin

It is a small protein molecule that inactivates several enzymes of the coagulation system. More

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Description

It is a small protein molecule that inactivates several enzymes of the coagulation system.

Generic Name

Antithrombin

Chemical names

FIBRIN, Fibrins, FIBRIN, TECH, AC1L96V8

Brand names

Atryn (International brand name)

IUPAC name

Pharmacokinetics

Actions

Antithrombin III is a glycoprotein with high molecular weight. It is present in the human plasma to inhibit the formation of thrombin. Antithrombin III can neutralize the serine protease to some extent. With an additive effect with heparin, Antithrombin III, the rate can be increased.

Dosage/Dosage form

The dosage and duration of Antithrombin therapy should be personalized and based on the circulatory levels of Antithrombin III and clinical condition.

Therapeutic uses

Used to treat Antithrombin III deficiency 

Adverse effects/Side effects

Abnormal levels of liver enzymes, nausea, vomiting, hives, chest pain, cramps, chills, flushing.

Interaction

Antithrombin moderately interacts with heparin and increases the risk of bleeding tendencies.

Contraindications

Storage

2-80C store in a refrigerator, do not freeze.

Information

Molecular weight

145.162 g/mol

Molecular formula

C5H11N3O2

CAS number

9001-31-4

Precautions

Monitor serological tests such hepatitis B and other infectious disease panels while and after receiving Antithrombin therapy.