Arsenic trioxide is an inorganic compound with the formula As 2O 3. This commercially important oxide of arsenic is the main precursor to other arsenic compounds, including organoarsenic compounds. More
Arsenic trioxide is an inorganic compound with the formula As 2O 3. This commercially important oxide of arsenic is the main precursor to other arsenic compounds, including organoarsenic compounds.
Arsenic trioxide
MFCD00003433, Arsenic (III) oxide, primary standard, Arsenic (III) oxide-18O3, Diarsenic trioxide
Arsenox, Arsikem, Arsitri, Riflux Tab
(arsoarsoroso) arsane
It is indicated for induction of consolidation and remission in patients with APL (acute promyelocytic leukemia) who are refractory to, or have relapsed from, retinoid and anthracycline chemotherapy.
0.15 mg/kg, IV, daily doses, up to 25 doses.
In Acute promyelocytic leukaemia (Intravenously).
Arsenic trioxide can cause cough, constipation, shortness of breath, joints pain, painful breathing, troubled sleeping fever, edema in the ankles or feet, diarrhoea, weight gain, hypokalemia, fatigue, myalgia, easy bruising, dry skin, weight loss, increased micturition, sore throat, hyperglycemia, mild rashes and vomiting.
Arsenic trioxide may interact narcotics, anti-depressants, ondansetron, clarithromycin, anti-arrhythmic drugs, diuretics, sumatriptan, anti-malarial drugs, chlorpromazine and droperidol.
Pregnancy; lactation; hypersensitivity
Store at 20-25°C.
197.84
As2O3
1327-53-3
It is contraindicated in patients with liver disease, renal disease, heart rhythm disorders including QT prolongation and electrolyte imbalance.
