Artesunate

Artesunate is a medication used to treat malaria. The intravenous form is preferred to quinidine for severe malaria.

Artesunate

Artesunate, AK128401, Beta-Artesunate, Artesunate [USAN: INN: BAN]

Artesunate, AK128401, Beta-Artesunate, Artesunate [USAN: INN: BAN]

4-oxo-4-{[(1R,4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0?,¹³.0?,¹³]hexadecan-10-yl]oxy}butanoic acid

2.4 mg/kg via IM or IV, repaeat after 12 and 24 hours later, thereafter daily once.

For the treatment of severe malaria (Falciparum malaria).

Transient and reversible reticulocytopaenia, bradycardia, drug fever, rash, transient 1st-degree heart block and reversible elevation of serum transaminases.

• Additive effect with chloroquine.
• Antimalarial potentiating action seen with mefloquine, primaquine and tetracycline. 
• Antagonistic effect with pyrimethamine and sulphonamides.

Hypersensitivity, pregnancy and lactation

Store in a dry and dark place

Molecular weight

384.425

Molecular formula

C19H28O8

CAS number

88495-63-0

Precautions

Hepatic or renal insufficiency