Azelaic acid

Azelaic acid is an organic compound with the formula HOOC(CH?)?COOH. This saturated dicarboxylic acid exists as a white powder. It is found in wheat, rye, and barley.

Azelaic acid

Azelaic acid; Finacea; Nonanedioic acid; Anchoic acid

Acnecbact, Aziderm, Acnezac Soap, Shaltop-A

nonanedioic acid

• Absorption: Systemically absorbed.
• Distribution: 43% protein binding
• Excretion: Urine

It inhibits the microbial cellular protein synthesis.

Apply thin film twice daily as a gel 15% or as a cream 20%.

For the topical treatment of mild-to-moderate inflammatory acne vulgaris.

Severe itching, changes in skin color, redness and peeling of skin, stinging or burning sensation.

• Digoxin and digitoxin may decrease the cardiotoxic activities of Azelaic Acid.
• The risk or severity of adverse effects can be increased when Docetaxel or Cabazitaxel is combined with Azelaic Acid.

Hypersensitivity

Store at 20-25°C.

Molecular weight

188.2209

Molecular formula

C9H16O4

CAS number

123-99-9

Precautions

• Azelaic acid should not be prescribed in patients with propylene glycol allergy.
• Occlusive dressings or wrappings should not be used.
• Avoid contact with eyes, mouth or other mucous membranes.
• Monitor for hypopigmentation in patients with dark complexion.
•  Recommend patient to use only very mild soaps or soapless cleansing lotions for facial washing.