Baclofen is a muscle relaxer used to treat muscle symptoms caused by multiple sclerosis, including spasm, pain, and stiffness. More
Baclofen is a muscle relaxer used to treat muscle symptoms caused by multiple sclerosis, including spasm, pain, and stiffness.
Baclofen-muscle relaxer used to treat muscle symptoms
Baclofen; Baclon; Lioresal; 4-Amino-3-(4-chlorophenyl)butanoic acid
Bacfen, Bacfen-XL, Baclan, Baclodol, Baclof, Baclof-OD, Bacmax, Chinofen, Joybac, Liofen, Liofen-XL, Lioresal, Parafon Dsc, Riclofen, Spinospas, Tefsole
4-amino-3-(4-chlorophenyl)butanoic acid
Baclofen is a direct agonist at GABAB receptors. The precise mechanism of action of Baclofen is not fully known, but it has capability to inhibit both polysynaptic and monosynaptic reflexes at the spinal level, possibly by hyperpolarization of afferent terminals, although actions at supraspinal sites may also occur and contribute to its clinical effect.
5mg three times a day for 3 days, it may be increased if needed.
Chronic spasticity
Ataxia, sedation, headache, drowsiness, dizziness, skin reactions, confusion, hallucinations, GI symptoms, and enuresis. Potentially Fatal: Respiratory or CV depression, seizures.
Hypotensive effect may be increased with antihypertensive.
Concomitant use with levodopa in Parkinson patients may result in confusion, agitation, hallucinations.
CNS depressants and alcohol may potentiate CNS effects.
Hypersensitivity.
Active peptic ulcer disease
Store below 25 ?
213.661
C10H12ClNO2
1134-47-0
Cerebrovascular disorders, epilepsy, severe psychotic disorders, respiratory depression, history of peptic ulcer, DM, pregnancy and hepatic or renal impairment.
Avoid sudden withdrawal.
