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Beclometasone-corticosteroid inhaler used to treat asthma

Beclometasone dipropionate, also spelled beclomethasone dipropionate and sold under the brand name Qvar among others, is a steroid medication. It is available as an inhaler, cream, pills, and nasal spray. More

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Description

Beclometasone dipropionate, also spelled beclomethasone dipropionate and sold under the brand name Qvar among others, is a steroid medication. It is available as an inhaler, cream, pills, and nasal spray.

Generic Name

Beclometasone-corticosteroid inhaler used to treat asthma

Chemical names

Beclomethasone; Beclometasone; Beclometasona; Beclometasonum

Brand names

Abicort Dps, Acderm, Adcort, Advin-NC, Aerocort, Aerocort Forte, Aerotide, Aerovent, Agrocure, Al-Dream, Alnabate, Aloderm-N

IUPAC name

2-[(1R,2S,10S,11S,13S,14R,15S,17S)-1-chloro-17-hydroxy-2,13,15-trimethyl-5-oxo-14-(propanoyloxy)tetracyclo[8.7.0.0²,?.0¹¹,¹?]heptadeca-3,6-dien-14-yl]-2-oxoethyl propanoate

Pharmacokinetics

Actions

Beclometasone, a synthetic halogenated glucocorticoid with antiinflammatory and vasoconstrictive effects, is used for treating steroid-dependent asthma, allergic or nonallergic rhinitis, or recurrent nasal polyps.

Dosage/Dosage form

  • Apply a 0.025% cream/ointment onto affected area for responsive dermatoses.
  • 100 mcg bid or 50 mcg 3-4 times daily in each nostril for allergic and non allergic rhinitis.
  • 250 mcg four times daily or 500 mcg bid for severe asthma.

Therapeutic uses

Adverse effects/Side effects

Loss of skin collagen and SC atrophy; local hypo pigmentation of deeply pigmented skin; dryness, irritation, epistaxis, rarely ulceration or perforation of the nasal septum; smell and taste disturbances; hoarseness and candidiasis of the mouth or throat.

Interaction

Contraindications

Hypersensitivity. Acute infections uncontrolled by antimicrobial chemotherapy.

Storage

Store at 15-30°C. 

Information

Molecular weight

521.042

Molecular formula

C28H37ClO7

CAS number

4419-39-0

Precautions

Active or doubtfully quiescent tuberculosis, paradoxical bronchospasm; children, elderly; pregnancy and lactation.