img

Bimatoprost- prostaglandin analog used topically to control the progression of glaucoma and in the management of ocular hypertension.

Bimatoprost is a prostaglandin analog used topically to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure by increasing the outflow of aqueous fluid from the eyes. More

Sharing is caring, show love and share the thread with your friends.

Description

Bimatoprost is a prostaglandin analog used topically to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure by increasing the outflow of aqueous fluid from the eyes.

Generic Name

Bimatoprost- prostaglandin analog used topically to control the progression of glaucoma and in the management of ocular hypertension.

Chemical names

Lumigan; Latisse; AGN 192024

Brand names

Bitoma, Careprost, Careprost Plus, Ganfort, Lumigan

IUPAC name

(5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl]-N-ethylhept-5-enamide

Pharmacokinetics

Actions

A synthetic structural analog of prostaglandin with ocular hypotensive activity, it mimics selectively the effects of naturally occurring substances, prostamides. Elevated IOP presents a major risk factor for glaucomatous field loss. This drug lowers intraocular pressure (IOP) in humans. The higher the level of IOP, the greater the likelihood of optic nerve damage and visual field loss.

Dosage/Dosage form

Bimatoprost 0.1 mg/mL or Bimatoprost 0.3 mg/mL ophthalmic solution.

Therapeutic uses

Indicated for open angle glaucoma and for intra ocular pressure.

Adverse effects/Side effects

Bimatoprost ophthalmic solution may cause vision changes, photophobia, itching/pain with redness of eyes, watery eyes, eye discomfort and dizziness, burning or stinging of eyes.

Interaction

Contraindications

Hypersensitivity

Storage

Store at 20-25°C.

Information

Molecular weight

415.5656

Molecular formula

C25H37NO4

CAS number

155206-00-1

Precautions

Bimatoprost ophthalmic solution may cause gradual brown discoloration of eyes or eyelids colour with increased growth of eyelashes. Colour change could be irreversible even after years of treatment discontinuation. Avoid overdose of Bimatoprost. It may result in drug tolerance.