Bupivacaine- local anesthetic medicinethat blocks the nerve impulses

Bupivacaine, marketed under the brand name Marcaine among others, is a medication used to decrease feeling in a specific area.

Bupivacaine- local anesthetic medicinethat blocks the nerve impulses

1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide; DL-Bupivacaine; Marcaine

Anawin Heavy, Anawin Inj, Buloc, Buloc-H, Buloc-P, Bupitroy, Bupitroy Heavy, Bupivac, Bupivacaine, Bupivan, Marcain, Sensorcaine, Sensorcaine Heavy, Sensorcaine Spinal

1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide

The recommended dose range is 25-150 mg.

In percutaneous infiltration anesthesia.

Cardiac and sudden respiratory arrest, depression. Hypotension, bradycardia, arrhythmias and cardiac arrest; methaemoglobinaemia; seizures, restlessness, dizziness. Hypersensitivity. Prolonged block.

• Hypersensitivity to local anaesthetics of amide type. IV regional anaesthesia; paracervical block in obstetrics; spinal anaesthesia <18 yr.
•  Solutions containing preservatives for caudal or epidural block.
• Lactation. 

Stored by health care providers in a refrigerator.

Molecular weight

288.4277

Molecular formula

C18H28N2O

CAS number

38396-39-3

Precautions

• Management includes careful and constant monitoring of CV and respiratory vital signs and the patient’s state of consciousness after each local anesthetic injections.
• Hypotension may also be managed by giving IV fluids such as sodium chloride injection.
• Establish and maintains a patent airway, oxygen may be needed. If necessary, drugs may be used to control convulsions.