A tricyclic antidepressant drug, the isobutyl side chain homologue of amitriptyline. More
A tricyclic antidepressant drug, the isobutyl side chain homologue of amitriptyline.
Butriptyline-Butriptyline is a tricyclic antidepressant
Butriptylene; Evadyne; Butriptyline [INN:BAN]
dimethyl(2-methyl-3-{tricyclo[9.4.0.0³,?]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}propyl)amine
Butriptyline possesses the anti-depressant property by inhibition of neuronal re-uptake of serotonin and norepinephrine. The tricyclic anti-depressant drug exerts weak sedating property.
25 mg of Butriptyline thrice daily, daily dose should not exceed 150 mg/day.
Anti depressant.
Butriptyline may interact with verapamil, disulfiram, diltiazem, cimetidine, adrenaline, amiodarone, SSRIs, thioridazine, propafenone, baclofen, MAOIs, sotalol, noradrenaline, estrogen, sibutramine, nitrates, carbamazepine, clonidine, terfenadine, procainamide, pimozide, opioid analgesics, sedatives, anti-muscarinics and anxiolytics. Do not consume alcohol while taking Butriptyline. It can cause serious adverse events.
Butriptyline is contraindicated in patients with porphyria, severe hepatic disorders, recent history of MI and CVD, behavioural disorders, seizures, urinary retention, close-angle glaucoma, diabetes, concurrent electroconvulsive therapy, pheochromocytoma and thyroid dysfunctions.
293.446 Da
C21H27N
35941-65-2
