Carbamoylcholine chloride (Carbachol)
2-[(Aminocarbonyl)oxy]-N,N,N-trimethylethanaminium chloride
Miostat
2-(trimethylazaniumyl) ethyl carbamate chloride
Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.
Carbachol has profound effects on both the cardiovascular system and the gastrointestinal system because of its ganglion-stimulating activity, and it may first stimulate and then depress these systems. It can cause release of epinephrine from the adrenal medulla by its nicotinic action. Locally instilled into the eye, it mimics the effects of acetylcholine, causing miosis and a spasm of accommodation in which the ciliary muscle of the eye remains in a constant state of contraction
Oral - Urinary retention
Adult: 2 mg tid.
Adult: Instill up to 0.5 ml of a 0.01% solution into the anterior chamber.
Adult: Instill up to 0.5 ml of a 0.01% solution into the anterior chamber.
Adult: 250 mcg, repeat twice if necessary at 30-min intervals.
Adult: 1-2 drops of a 0.75-3% solution up to 4 times daily, usually in conjunction with other miotics.
As miotic agent to treat glaucoma by causing pupillary contraction and a decrease in intraocular pressure.
Nausea, abdominal pain, sweating, vomiting, flushing, salivation, diarrhea, eructation, headache, urinary frequency, blurred vision, myopia, conjunctival vascular congestion, ocular burning, itching.
NSAIDs.
During pregnancy, Cardiac diseases, Asthma, Peptic ulcer
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
182.65
C6H15ClN2O2
51-83-2
Parkinson's disease, Hypertension
