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DPT vaccine/DTP and DTwP vaccine- refers to a class of combination vaccines against three infectious diseases in humans

DPT (also DTP and DTwP) refers to a class of combination vaccines against three infectious diseases in humans More

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Description

DPT (also DTP and DTwP) refers to a class of combination vaccines against three infectious diseases in humans

Generic Name

DPT vaccine/DTP and DTwP vaccine- refers to a class of combination vaccines against three infectious diseases in humans

Chemical names

NA

Brand names

Adacel, Boostrix, Diphtheria, Tetanus, Pertussis, Easy-4, Easy-5, Ecovac, Infanrix, Pentavac, Tripacel, Triple Antigen, Triple-Antigen, Tripvac

IUPAC name

NA

Pharmacokinetics

NA

Actions

The vaccine components include diphtheria and tetanus toxoids, and killed whole cells of the organism that causes pertussis (wP).

Dosage/Dosage form

It comes in solution for injection.

Therapeutic uses

Immunizing agent

Adverse effects/Side effects

Pain, swelling and redness at the injection site. Fever, headache, fatigue and GI symptoms e.g. nausea, diarrhoea, abdominal pain.

Interaction

Immune response to vaccines may be reduced in patients who are receiving immunosuppressive treatment e.g. cytotoxics, high dose corticosteroids, irradiation.

Contraindications

  • History of encephalopathy within 7 days of vaccination with pertussis-containing vaccine.
  • Hypersensitivity.
  • Vaccine should not be used in patients with progressive neurologic disorder, progressive encephalopathy or uncontrolled epilepsy.

Storage

Store at 2-8°C.

Information

Molecular weight

NA

Molecular formula

NA

CAS number

NA

Precautions

  • Not to be used in patients with bleeding disorders or patients on anticoagulant treatment unless benefit outweighs risk.
  • Caution when used in patients with family history of seizures or other CNS disorders.
  • Pregnancy and lactation.