Echothiophate
Phospholine, Ecothiopatum
Phospholine Iodide
diethyl {[2-(trimethylazaniumyl)ethyl]sulfanyl}phosphonate
Absorbed systemically
Echothiophate Iodide is a long-acting cholinesterase inhibitor for topical use which enhances the effect of endogenously liberated acetylcholine in iris, ciliary muscle, and other parasympathetically innervated structures of the eye. Echothiophate iodide binds irreversibly to cholinesterase, and is long acting due to the slow rate of hydrolysis by cholinesterase. It causes miosis, increase in facility of outflow of aqueous humor, fall in intraocular pressure, and potentiating of accommodation.
Ophthalmic medication
Used in the treatment of glaucoma
Blurred vision, eye pain
Echothiophate may increase the bradycardic activities of Alprenolol, Acebutolol.
Do not use for tonometric glaucoma
Room temperature
256.321 g/mol
C9H23NO3PS
6736-03-4