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Gemeprost

Gemeprost is an analogue of prostaglandin E?. More

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Description

Gemeprost is an analogue of prostaglandin E?.

Generic Name

Gemeprost

Chemical names

Gemeprost; Carprost; UNII-45KZB1FOLS; Cervagem

Brand names

NA

IUPAC name

methyl (2E)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4,4-dimethyloct-1-en-1-yl]-5-oxocyclopentyl]hept-2-enoate

Pharmacokinetics

NA

Actions

Gemeprost softens and dilates of the cervix prior to transcervical intrauterine operative procedures. It is a prostaglandin E1 analog that potently stimulates uterine contractions and causes cervical ripening and relaxation

Dosage/Dosage form

NA

Therapeutic uses

NA

Adverse effects/Side effects

NA

Interaction

Gemeprost may fatally interact with oxytocin and other uterotonic drugs.

Contraindications

NA

Storage

Store below -15°C.

Information

Molecular weight

394.552

Molecular formula

C23H38O5

CAS number

64318-79-2

Precautions

This is contraindicated in patients with vaginitis, elevated IOP, COPD, unexplained vaginal bleeding, cervicitis, CV insufficiency, uterine scarring and placenta previa.