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Glucosamine

Glucosamine is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. More

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Description

Glucosamine is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids.

Generic Name

Glucosamine

Chemical names

Glucosamine; D-Glucosamine; 2-Amino-2-Deoxy-D-Glucopyranose; 2-Amino-2-Deoxy-D-Glucose; Chitosamine

Brand names

Acijoint, Admine, Alcerine-G, Alnamax-G, Alnamax-GM, Altocerin-GM, Arcerin-GM, Arine-GM, Aronix-M, Arth Softlets, Arthar, Arthcure-D, Artheal, Arthocare, Arthocerin-G, Arthodia-G, Arthrovit Plus, Artica, Artifix, Artilage, Baknil, Bigjoint, Biocerine-GM, Biojoynt, Biostan-D, Biovit-D, Bonit Join, Bonjo Aid, Bontom-G, Carticare, Cartiel, Cartifix, Cartigen, Cartigen Oint, Cartigen Plus, Cartigen Sachet, Cartiglow-GM, Cartilamine, Cartilamine Forte, Cartilamine Total, Cartilamine-DS, Cartilamine-SR, Cartimost-GM, Cartipro, Cartirich-GM, Cartisafe Forte, Cartisark, Cartispan, Cartivit, Cartiwel

IUPAC name

(3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol

Pharmacokinetics

NA

Actions

Osteoarthritis is characterized by the progressive degeneration of cartilage glycosaminoglycans. Glucosamine is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Since glucosamine is a precursor for glycosaminoglycans. They are a major component of joint cartilage, supplemental glucosamine may help to rebuild cartilage and treat arthritis. Its use as a therapy for osteoarthritis appears safe, but there is conflicting evidence as to its effectiveness with more recent studies showing limited to no clinical benefit of use.

Dosage/Dosage form

500 mg 3-4 times daily PO.

Therapeutic uses

Glucosamine is usually used in the treatment of osteoarthritis and Rheumatoid arthritis.

Adverse effects/Side effects

Heart burn, epigastric pain/tenderness, diarrhoea, nausea, dyspepsia, constipation, abdominal pain, palpitations, drowsiness, skin reaction, headache, indigestion.

Interaction

NA

Contraindications

Allergy to shellfish.

Storage

Store in cool place and in an airtight container.

Information

Molecular weight

179.1711

Molecular formula

C6H13NO5

CAS number

3416-24-8

Precautions

  • It may cause drowsiness, do not drive a car or operate machinery while taking this medication. 
  • Caution should be exercised in patients with any allergy, history of diabetics, children, during pregnancy and breastfeeding. 
  •  It may affect blood sugar level; monitor sugar level regularly while taking this medication.