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Human menopausal Gonadotropin

Menotropin is a hormonally active medication for the treatment of fertility disturbances. Frequently the plural is used as the medication is a mixture of gonadotropins. Menotropins are extracted from the urine of postmenopausal women. More

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Description

Menotropin is a hormonally active medication for the treatment of fertility disturbances. Frequently the plural is used as the medication is a mixture of gonadotropins. Menotropins are extracted from the urine of postmenopausal women.

Generic Name

Human menopausal Gonadotropin

Chemical names

NA

Brand names

Evahope-M HP, Follilutin, Follinis, Humog, Materna HMG, Menodac, Menolife, Menonys, Menotec, Menovul, Ovugraf-HP, Ovulate-M, Persinal-HP, Pregnorm, Proferti-H, Zy- HMG

IUPAC name

NA

Pharmacokinetics

NA

Actions

The action of HCG is virtually identical to that of pituitary LH, although HCG appears to have a small degree of FSH activity as well. It stimulates production of gonadal steroid hormones by stimulating the interstitial cells (Leydig cells) of the testis to produce androgens and the corpus luteum of the ovary to produce progesterone.

Dosage/Dosage form

NA

Therapeutic uses

NA

Adverse effects/Side effects

Ovarian hyperstimulation, risk of multiple pregnancy and miscarriage, hypersensitivity and local reactions at Inj site, nausea, vomiting, joint pain, fever. In men, gynecomastia, acne, weight gain. Rupture of ovarian cysts and intraperitoneal haemorrhage.

Interaction

Drugs with luteinising hormone activity may increase risk of ovarian hyperstimulation syndrome.

Contraindications

Ovarian cysts or enlargement not caused by polycystic ovarian syndrome; tumors of breast, uterus, ovaries, testes or prostate; vaginal bleeding of unknown cause; pregnancy and lactation.

Storage

NA

Information

Molecular weight

NA

Molecular formula

NA

CAS number

9002-61-3

Precautions

Hyperprolactinemia or tumors of the pituitary or hypothalamus. Ovarian enlargement at risk of rupture, care in pelvic examinations. Risk of multiple births.