Hydroxyapatite

Hydroxylapatite, also called hydroxyapatite, is a naturally occurring mineral form of calcium apatite with the formula Ca?(PO?)?, but is usually written Ca??(PO?)?(OH)? to denote that the crystal unit cell comprises two entities.

Hydroxyapatite

Durapatite; Hydroxylapatite; Alveograf; Periograf

: Calcizin, Calex-1000, Calfort, Calstat Syr, Calstron, Mycal, Natcal, Natcal Susp, Natcal-1000, Natucal, Odical, Orgacal, Ossopan, Ossopan Susp, Ossopan-1000, Ossopan-500, Ossopan-D, Tuf-Cal

Calciumhydroxidphosphat (5:1:3)

NA

NA

1660 mg bid.

Prophylaxis of postmenopausal osteoporosis

Risk of hypercalciuria

Biphosphonates may increase the osteoconductive and regenerative properties of hydroxyapatite when used together.

Hypersensitivity. Children <6 yr. Prolonged immobilization accompanied by hypercalciuria

NA

Molecular weight

502.311 Da

Molecular formula

HCa5O13P3

CAS number

1306-06-5

Precautions

• Monitor serum calcium level during treatment. To be taken with vitamin D for maximal benefit.
• Caution when used in renally impaired patients.