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Hydroxyethyl starch

Hydroxyethyl starch, sold under the brand name Voluven among others, is a nonionic starch derivative, used as a volume expander in intravenous therapy. More

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Description

Hydroxyethyl starch, sold under the brand name Voluven among others, is a nonionic starch derivative, used as a volume expander in intravenous therapy.

Generic Name

Hydroxyethyl starch

Chemical names

2-Hydroxyethyl starch; Hydroxyethyl starch; 9005-27-0; (C6H10O5)m(C2H5O)n; Hydroxyethylated amylopectin

Brand names

Expan, Haes-Steril, Hestar, Pentarch, Perfusol, Tetrahes, Tetraspan, Venofundin, Volulyte

IUPAC name

2-Hydroxyethyl 2,3,4,6-tetrakis-O-(2-hydroxyethyl)-?-D-glucopyranoside - ?-D-glucopyranose (1:1)

Pharmacokinetics

NA

Actions

NA

Dosage/Dosage form

NA

Therapeutic uses

Used to prevent shock following severe blood loss caused by surgery, trauma or other issues.

Adverse effects/Side effects

Hydroxyethyl starch can cause anaphylactoid reactions including tachycardia, non-cardiac pulmonary edema and bronchospasms. 

Interaction

NA

Contraindications

NA

Storage

Store at room temperature

Information

Molecular weight

580.575 Da

Molecular formula

C22H44O17

CAS number

9005-27-0

Precautions

Fluid status and infusion rates should be carefully monitored in severe renal dysfunction, severe hepatic disorders, severe bleeding disorders and cardiac insufficiency patients.