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Imiquimod

Imiquimod is a prescription medication that acts as an immune response modifier and is used to treat genital warts, superficial basal cell carcinoma, and actinic keratosis. More

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Description

Imiquimod is a prescription medication that acts as an immune response modifier and is used to treat genital warts, superficial basal cell carcinoma, and actinic keratosis.

Generic Name

Imiquimod

Chemical names

IMIQUIMOD; 99011-02-6; Aldara; Zyclara; 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine

Brand names

Imiquad, Nilwart

IUPAC name

1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine

Pharmacokinetics

NA

Actions

Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. It is an immune response modifier acts as a receptor 7 toll-like agonist. Imiquimod does not cure warts, and new warts may appear during treatment. This is also used to treat actinic keratoses (a skin condition of the scalp and face). Imiquimod can also be used to treat superficial basal cell carcinoma (type of skin cancer). 

Dosage/Dosage form

Topical: Apply a thin layer of this cream 2 times per week for 16 weeks.

Therapeutic uses

For the treatment of nonhypertrophic, nonhyperkeratotic external perianal and genital warts/condyloma acuminata actinic keratoses on the face or scalp in immunocompetent adults. 

Adverse effects/Side effects

Severe swelling, urination problems, cold sores, fever, blisters, vaginal discharge, nausea, diarrhoea, blisters, changes in treated skin, mild skin irritation, flaking, scabbing, crusting, hardening and dryness.

Interaction

NA

Contraindications

This drug is contraindicated in patients with immune dysfunctions, skin problems, autoimmune disorders, sunburns, organ transplanted patients, GVHD. 

Storage

Store at 20-25°C.

Information

Molecular weight

240.3036

Molecular formula

C14H16N4

CAS number

99011-02-6

Precautions

  • Avoid application of Imiquimod with lips, eyes, mouth or nose.
  •  This drug should not be prescribed in patients with actinic keratosis or genital warts with surgery that were recently treated.
  •  Avoid unprotected sex
  • Don’t apply this drug on rectum, irritated skin, urethra, sunburns and vagina.
  • Avoid direct exposure to sunlight while using Imiquimod.