Inositol nicotinate

Inositol nicotinate is a vasodilator. Inositol Nicotinate is given the term Inositol hexaniacinate, as well as "No-Flush Niacin".

Inositol nicotinate

Inositol niacinate; Inositol nicotinate; Inositol hexanicotinate; Myo-Inositol hexanicotinate

NA

(1R,2S,3R,4R,5S,6s)-2,3,4,5,6-pentakis(pyridine-3-carbonyloxy)cyclohexyl pyridine-3-carboxylate

NA

Inositol nicotinate mediates a vasodilatory, lipid-lowering and fibrinolytic effect on the cardiovascular system. It is a lipid-regulating agent, reduces the levels of apoB (atherogenic apolipoprotein B)-containing lipoproteins (VLDL, LDL and lipoprotein a), plasma triglycerides while increasing antiatherogenic apoA-I-containing HDL levels.

The recommended oral daily dosage is 1500-4000 mg of Inositol nicotinate in 2-4 divided doses.

Indicated as a dietary supplement for the source of niacin.

NA

• Moderate level of drug interact was reported with anticoagulants, salicylates, transdermal nicotine patches, statins and NSAIDs.
• This drug can interact with pioglitazone, glimepiride, insulin and tolbutamide (anti-diabetic drugs).

This is contraindicated in patients with gallbladder disorders, bleeding disorders, gout, allergies, hypotension, angina, peptic ulcer with or without perforations, CAD and diabetes.

NA

Molecular weight

810.732

Molecular formula

C42H30N6O12

CAS number

6556-11-2

Precautions

Inositol nicotinate should not be prescribed to individuals who are allergic to synthetic form of niacin.