Iron polymaltose

Iron polymaltose is a water soluble, macro-molecular complex of iron (III) hydroxide and isomaltose.

Iron polymaltose

Ferrummate; Amylofer; Maltofer

3-Up SYR, 3-Up TAB, Acmetose, Addfer, Bodyred-IPC, Carbiran, Carbiran DPS, Carbofen, Carzin-IPC, Cheri, Facer, Fefa, Fefa SYR, Fegem, Fegem Tab, Femed, Femed SYR, Fericip, Ferrasia, Ferro Hepatine, Ferron, Folinal Plus, Gilfer, Polyfer SYR, Rigovit Powd, Synhafm-L, Synhafm-S, Trifer Dps, Trifer SYR, Zenglobin SYR

iron(3+);(2R,3S,4R,5R)-2,3,4,5-tetrahydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanal;trihydroxide

NA

NA

NA

It is used in the treatment of iron-deficiency anaemia.

GI irritation, Joint and muscle pain, pain at injection site, epigastric pain, stomach cramping, constipation, nausea, vomiting, diarrhoea, dark stools, heart burn, discoloured urine, teeth staining, bronchospasm, hypotension, tachycardia, flushing, sweating, dizziness.

NA

• Hypersensitivity
• Disturbances in iron utilisation, thalassemia.
• Patients receiving repeated blood transfusion.
• Iron overload, chronic polyarthritis, Ostler-Rendu-Weber syndrome, bronchial asthma, uncontrolled hyperparathyroidism, inflammation or infection of kidney or liver, decompensated liver cirrhosis. Pregnancy (1st trimester).

Store below 25°C.

Molecular weight

449.163 g/mol

Molecular formula

C12H25FeO14

CAS number

53858-86-9

Precautions

• Avoid concomitant parenteral and oral iron administration, oral iron therapy should start at least 1 week after last iron injection.
• Pregnancy (2nd and 3rd trimester), allergies, hepatic and liver insufficiency, low iron binding capacity and or folic acid deficiency.
• Facilities for CPR should be available during administration.
• Concurrent use with psychotropic drugs may worsen constipation.
• Excessive IV infusion rate may cause epigastric upset and nausea.