Ivabradine

It is a medication used for the symptomatic management of stable heart-related chest pain and heart failure not fully managed by beta blockers.

Ivabradine

Ivabradine; Corlanor; Procoralan; 155974-00-8; Corlentor

Coralan, Bradia, Inapure, Ivabrad, Ivabid, Ivanode, Ivazine

3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one

NA

NA

The recommended dose is 5 mg twice daily. Increase if necessary to 7.5 mg twice daily after 3-4 weeks. It may be reduced up to 2.5-5 mg twice daily if needed.

This medication is a cardio tonic agent, prescribed for angina pectoris. It helps to lower the heart rate

Slow heart rate, palpitations, heart block, abnormal heart rhythm, difficulty in breathing and fainting. Muscle cramps and muscle weakness.

• Ivrbradine may interact with St. John’s Wort and other similar herbs.
• Ivabradine may interact with Amiodarone, cisapride, erythromycin, sotalol, antipsychotics, anti-fungal drugs, calcium-channel blockers, rifampicin, phenobarbital, macrolide antibiotics, protease inhibitors (anti-retroviral drugs), phenytoin, nefazodone and anti-malarial drugs.

Contraindicated in patients with running nose, hepatic impairment, hypertension, allergy, arrhythmia, atrial flutter and fluctuating ocular pressure.

Store it at room temperature (25°C).

Molecular weight

468.594

Molecular formula

C27H36N2O5

CAS number

155974-00-8

Precautions

• Do not drive vehicles or operate heavy machineries while taking Ivrabradine.
• Avoid consumption of grape wine, grapefruit and grapefruit juice while taking Ivrabradine.