Ketamine-categorized as a “dissociative anesthetic

Ketamine is a type of medication used to induce loss of consciousness (anesthesia), produce relaxation

Ketamine-categorized as a “dissociative anesthetic

Ketamine; Ketaject; Ketalar; Dl-Ketamine; Ketanest

Aneket, Hypnoket, Keta, Ketafast, Ketajet, Ketajex, Ketalar, Ketam, Ketamax, Ketmin, Ketriplin, Ketsia, Kmin, Taurket

2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one

Parenteral absorption with a hepatic metabolism, excreted via urine.

1-4.5 mg/kg as IV, 0.5-2 mg/kg as IV infusion, 6.5 to 13 mg/Kg IM.

Anesthetic agent

Vivid dreams, hallucinations, confusion, and irrational behaviour. Increased muscle tone sometimes resembling seizures. Temporary hypertension and tachycardia. Hypotension, bradycardia, arrhythmias. Respiratory depression, apnoea, laryngospasm, diplopia, nystagmus, nausea, vomiting, lachrymation, hypersalivation, raised intraocular and CSF pressure, skin rash and pain at injection site.

• May increase effects of nondepolarising muscle relaxants.
• May reduce hypnotic effect of thiopental.
• Prolonged recovery time with barbiturates/narcotics.
• Reduced BP, cardiac output, and pulse rate with halothane.
• Increased risk of hypertension and tachycardia with thyroid hormones.
• Seizures and tachycardia may occur when used with theophyllines.

Hypertension, history of cerebrovascular accident. Eye injury, raised ocular and intracranial pressure. Psychotic disorders.

Store at 15-30 ? 

Molecular weight

237.725

Molecular formula

C13H16ClNO

CAS number

6740-88-1

Precautions

• Minimise verbal and tactile stimulation during recovery period.
• Chronic alcoholic and alcohol-intoxicated patients.
• Preanaesthetic elevated CSF pressure.
• Dependence and tolerance may develop.
• May impair ability to drive or operate machinery.
• Monitor cardiac function in patients with cardiac decompensation or hypertension.
• Pregnancy and lactation.