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Ornidazole- drug that cures some protozoan infections.

Ornidazole is a drug that cures some protozoan infections. It has been investigated for use in Crohn's disease after bowel resection More

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Description

Ornidazole is a drug that cures some protozoan infections. It has been investigated for use in Crohn's disease after bowel resection

Generic Name

Ornidazole- drug that cures some protozoan infections.

Chemical names

Ornidazole; Madelen; Tiberal; 1-(3-Chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole

Brand names

Aurnida, Cgdole, Dazolic, Entamizole Plus, Fern, Gazal-O, Giro, Horn, Kooz, Lumigard, Metrogyl Gel Plus, Nidazole, Nidoba, Obit-OZ, Ofnida-LB, Olife-OZ, Onidaz, Oniz, Orbest, Ord, Orni, Ornida, Orniden, Ornilet, Ornimax, Ornivir, Ornizen, Osani-O, Sayoflox-OZ, Sigmadys-OZ, Zil

IUPAC name

1-Chloro-3-(2-methyl-5-nitro-1H-imidazol-1-yl)-2-propanol

Pharmacokinetics

Actions

Dosage/Dosage form

The recommended dose is 0.5g-1.5g daily for 1-7 days as PO.

Therapeutic uses

Used to treat protozoan infections

Adverse effects/Side effects

Somnolence, headache, nausea, vomiting, dizziness, tremor, rigidity, poor coordination, seizures, tiredness, vertigo, temporary loss of consciousness & signs of sensory and mixed peripheral neuropathy, taste disturbances, abnormal LFTs, skin reactions.

Interaction

  • Potentiates effect of couramin- type oral anticoagulants.
  • Prolongs the muscle- relaxants effect of vecuronium bromide.

Contraindications

Hypersensitivity

Storage

Store it at room temperature.

Information

Molecular weight

219.626 Da

Molecular formula

C7H10ClN3O3

CAS number

16773-42-5

Precautions

  • May impair ability to drive or operate machinery.
  • Renal & hepatic impairment.
  • CNS diseases e.g epilepsyor multiple sclerosis.
  • Pregnancy & lactation.