Ramosetron Hydrochloride

Ramosetron (INN) is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting

Ramosetron Hydrochloride

Ramosetron; 132036-88-5; UNII-7ZRO0SC54Y; Ramosetron [INN]; CHEMBL1643895; Ramosetron (INN)

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(5R)-5-(1-methyl-1H-indole-3-carbonyl)-4,5,6,7-tetrahydro-1H-1,3-benzodiazole

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5 mcg of Ramosetron hydrochloride once daily. The maximum daily dose should not exceed 10 mcg.

For the treatment of nausea and vomiting and diarrhea-predominant irritable bowel syndrome in males.

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• Co administration of Ramosetron hydrochloride with MAOIs, CYP1A2 inhibitors, anti-psychotics, tricyclic anti-depressant drugs, phenothiazines, anti-cholinergics and opioid narcotics results in serious and severe GI disturbances including diarrhoea or constipation.

• Ramosetron hydrochloride is contraindicated in patients with active diarrhoea, predominant irritable bowel syndrome, infectious enteritis, colon cancer, constipation colitis, patients unresponsive to conventional therapy.
• Ramosetron hydrochloride is contraindicated in patients with hypersensitivity to Ramosetron hydrochloride.

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Molecular weight

279.343

Molecular formula

C17H17N3O

CAS number

132036-88-5

Precautions

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