Riluzole

Riluzole is a drug used to treat amyotrophic lateral sclerosis. Riluzole delays the onset of ventilator-dependence or tracheostomy in selected patients and may increase survival by approximately two to three months.

Riluzole

Riluzole; 1744-22-5; Rilutek; 2-Amino-6-(trifluoromethoxy)benzothiazole; 6-(trifluoromethoxy)benzo[d]thiazol-2-amine

Rilutor

6-(trifluoromethoxy)-1,3-benzothiazol-2-amine

Well absorbed orally, plasma protein bound 96%.

Riluzole, a member of the benzothiazole class, is indicated for the treatment of patients with amyotrophic lateral sclerosis (ALS). Riluzole extends survival and/or time to tracheostomy.

The recommended dose is 50 mg orally every 12 hours.

For the treatment of amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease)

Tiredness, muscle weakness, difficulty in breathing, fever. Upset stomach, diarrhea, and loss of appetite. 

• Drugs such as acetaminophen, anti-cancer drugs, live vaccines, allopurinol, omeprazole, amitriptyline, auranofin, anti-tubercular drugs, methyldopa, omeprazole, OCPs, methotrexate, erythromycin, theophylline, ciprofloxacin, sulfasalazine, methyldopa, niacin, ACE inhibitors, statins, anti-retroviral drugs, NSAIDs and anti-convulsant drugs riluzole may interacted.

Riluzole is contraindicated in patients with renal or hepatic diseases. Do not receive live virus vaccine while using Riluzole.

Store at 20-25°C.

Molecular weight

234.198

Molecular formula

C8H5F3N2OS

CAS number

1744-22-5

Precautions

To avoid liver damage, do not drink alcoholic beverages.