Risedronic acid or Risedronate sodium

Risedronic acid (INN) often used as its sodium salt risedronate sodium (USAN) is a bisphosphonate used to strengthen bone, treat or prevent osteoporosis, and treat Paget's disease of bone.

Risedronic acid or Risedronate sodium

Risedronate; Risedronic acid; 105462-24-6; Atelvia; Risedronate sodium

Actonel, Fossical, Gemfos, Osteodronate, Resica, Risofos, Risofos Kit, Ritomune

[1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethyl]phosphonic acid

NA

This drug will inhibit the osteoclast-mediated bone resorption and modulates bone metabolism and is indicated for the prevention and treatment of osteoporosis in postmenopausal women.

NA

For the treatment of Paget's disease of the bone (osteitis deformans), postmenopausal and glucocorticoid-induced osteoporosis

Electrolyte disturbances; GI disturbances; musculoskeletal pain; headache; hypersensitivity reactions; blood disorders; liver enzyme disturbances. Bone, joint and/or muscle pain.

• Co-admin with calcium, antacids or oral medications containing divalent cations may affect the absorption of risedronate.
• May have additive calcium lowering effects when used with aminoglycosides.

• Pregnancy
• Acute upper GI inflammation,
• Hypocalcaemia

Store at 20-25°C

Molecular weight

283.1123

Molecular formula

C7H11NO7P2

CAS number

105462-24-6

Precautions

• Correct hypocalcaemia prior to therapy.
• Renal impairment
• Monitor hepatic and renal function and WBC.