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Ritodrine hydrochloride

Ritodrine is a tocolytic drug used to stop premature labor. More

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Description

Ritodrine is a tocolytic drug used to stop premature labor.

Generic Name

Ritodrine hydrochloride

Chemical names

Ritodrine hydrochloride; 23239-51-2; RITODRINE HCL; Ritodrine; Ritodrinehydrochloride

Brand names

Miolene, Ristore, Ritodine, Ritolan, Ritopar-UR, Ritrod, Tocopar, Uterelax, Utgard, Utodin, Utowin, Yutodian, Yutopar

IUPAC name

4-(2-{[(1R,2S)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]amino}ethyl)phenol

Pharmacokinetics

NA

Actions

Beta-2 adrenergic receptors are located at sympathetic neuroeffector junctions of many organs, including uterus. Ritodrine is beta-2 adrenergic agonist. 

Dosage/Dosage form

NA

Therapeutic uses

For the treatment and prophylaxis of premature labour

Adverse effects/Side effects

Tachycardia, palpitation, headache, nervousness, anxiety, nausea, vomiting.

Interaction

  • Neuromuscular blockade produced by vecuronium and pancuronium May enhance by ritodrine.
  • Potassium-depleting drugs may increase risk of hypokalaemia.

Contraindications

Cardiac disease, cord compression, eclampsia and severe preeclampsia, intrauterine foetal death, placenta praevia, threatened miscarriage and antepartum haemorrhage.

Storage

Normally handled and stored by health care providers.

Information

Molecular weight

287.3535

Molecular formula

C17H21NO3

CAS number

26652-09-5

Precautions

  • DM, hypertension, concurrent steroids, myocardial insufficiency, hyperthyroidism, arrhythmias, CV risk factors, and bronchial asthma treated with beta-agonists, lactation.
  • Monitor maternal pulse, plasma glucose and potassium.
  • Monitor patient's hydration status to reduce risk of pulmonary oedema. Discontinue treatment if there are signs of pulmonary oedema.