Rocuronium bromide (brand names Zemuron, Esmeron) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate tracheal intubation by providing skeletal muscle relaxation, most commonly required for surgery or mechanical ventilation. More
Rocuronium bromide (brand names Zemuron, Esmeron) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate tracheal intubation by providing skeletal muscle relaxation, most commonly required for surgery or mechanical ventilation.
Rocuronium
Rocuronium; 143558-00-3; UNII-WRE554RFEZ; CHEBI:8884; WRE554RFEZ
Zemuron (International)
1-[(1S,2S,4S,5S,7S,10R,11S,13S,14R,15S)-14-(acetyloxy)-5-hydroxy-2,15-dimethyl-4-(morpholin-4-yl)tetracyclo[8.7.0.0²,?.0¹¹,¹?]heptadecan-13-yl]-1-(prop-2-en-1-yl)pyrrolidin-1-ium
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IV- The recommended initial dose regardless of anesthetic technique is 0.6 mg/kg. Maintenance: 0.1, 0.15, and 0.2 mg/kg.
A muscle-relaxant is used as a general anaesthesia prior to a surgical procedure.
Abnormal heart rhythm, abnormal electrocardiogram and fast heart rate. Rash, injection site swelling and itching.
Interacted with amikacin, anti-convulsant drugs, polymyxin-B, antacids and mineral supplements containing magnesium salts, lithium, procainamide, tetracycline, corticosteroids, kanamycin, neomycin, vancomycin and streptomycin and tobramycin.
Rocuronium is contraindicated in patients with myasthenia gravis, renal disorders, heart problems, prolonged QT waves, renal diseases, cirrhosis, circulatory problems and allergy to anaesthetics.
Store at 20-25°C.
529.7742
C32H53N2O4
143558-00-3
Avoid excess dosage.
