Typhoid vaccine

Typhoid vaccines are vaccines that prevent typhoid fever. There are two types that are widely available: Ty21a and Vi capsular polysaccharide vaccine

Typhoid vaccine

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Biovac Typhoid, Peda-Typh, Shantyph, Typbar, Typherix, Typhim-VI, Typhivax, Typho-VI, Typhoral, Tyvax VI- Plus, Tyvax VI- Plus 150 MCG, Vactyph

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Oral, IM

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Headache, fever, rash, abdominal pain, nausea, diarrhoea, vomiting, anaphylactic reaction, demyelinating disease, myalgia, pain, urticaria, sepsis and weakness. Fever, headache, malaise, injection-site reactions (such as pain, tenderness and swelling), nausea, vomiting.

• Concurrent use with immunosuppressants may increase the adverse effects of live vaccines.
• Avoid alcohol within 2 hours of consuming the capsule.
• May reduce the diagnostic effect of tuberculin tests.
• Mefloquine may increase the efficacy of typhoid vaccine.
• Concurrent use with immunoglobulins or antibiotics may reduce the efficacy of typhoid vaccine. 

• Vaccination should be postponed in patients with acute febrile illness or acute GI illness. Oral vaccine:
• Not to be used in acquired or congenital immunodeficient state, including patients receiving antimitotic drugs or immunosuppressive.

Store between 2-8°C.

Molecular weight

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Molecular formula

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CAS number

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Precautions

• Monitor patient for possible adverse reactions. Report suspected adverse reactions following immunization to the Department of Health and Human Services Vaccine Adverse Event Reporting System.
• Not for treatment of typhoid fever.
• Vaccination may not provide full proetction thus, travellers should be advised to take all necessary precautions to avoid contact or ingestion of potentially contaminated food or water sources. IM admin:
• Caution when used in patients with a history of bleeding disorders, patients on anticoagulant treatment or severely immunocompromised patients.
• Pregnancy, lactation.