Valganciclovir

Valganciclovir, sold under the brandname Valcyte among others, is an antiviral medication used to treat cytomegalovirus infection in those with HIV/AIDS or following organ transplant.

Valganciclovir

Valganciclovir; Cymeval; Valganciclovir [INN:BAN]; 175865-60-8; UNII-GCU97FKN3R

Valcyte, Valgan

2-[(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]-3-hydroxypropyl (2S)-2-amino-3-methylbutanoate

Well absorbed from the GI (Gastrointestinal).

It is actually a prodrug for ganciclovir. Valganciclovir is an antiviral medication used to treat cytomegalovirus infections. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases. After this, it (being an analogue of guanosine) gets incorporated into DNA and thus cannot be properly read by DNA polymerase. This results in the termination of the elongation of viral DNA.

The recommended dose is 900 mg twice a day for 21 days per oral.

Used for the treatment of cytomegalovirus infections.

Seizure, light-headedness, rapid heartbeats, troubled breathing, fever, chills, seizure, weight gain, diarrhoea, tremors, drowsiness, easy bruising, urination changes, flu-like symptoms, anorexia, polydipsia, GI changes and pale skin.

• Valganciclovir may interact with didanosine, ganciclovir, mycophenolate, probenecid and zidovudine.
• Avoid consumption of alcohol while taking Valganciclovir

Hypersensitivity

Store at room temperature away from moisture and heat.

Molecular weight

354.3617

Molecular formula

C14H22N6O5

CAS number

175865-60-8

Precautions

• Valganciclovir should not be prescribed to dialysis-dependent renal disorder patients, liver diseases, anemia and patients on corticosteroids or radiation therapy.
• Valganciclovir can impair thinking and mental alertness.
• Do not drive vehicles or operate heavy machineries while taking Valganciclovir.
• Avoid close contact with sick/infected people.

Avoid outdoor activities that can cause injury or bleeding risks.