It is a detergent or solvent treated sterile liquid preparation of purified IgG (human immune globulin G) containing antibodies to varicella zoster virus (anti-VZV). It is prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and was approved in 2012 under the name VariZIG to reduce the disease severity in high-risk patients who lack evidence of immunity to varicella and for whom varicella vaccine is contraindicated. The therapeutic efficacy is proven if administered within 4 days of exposure to varicella zoster virus. More
It is a detergent or solvent treated sterile liquid preparation of purified IgG (human immune globulin G) containing antibodies to varicella zoster virus (anti-VZV). It is prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and was approved in 2012 under the name VariZIG to reduce the disease severity in high-risk patients who lack evidence of immunity to varicella and for whom varicella vaccine is contraindicated. The therapeutic efficacy is proven if administered within 4 days of exposure to varicella zoster virus.
Varicella-zoster immunoglobulins
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Okavax, Varilrix, Vartiect-CP
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NA
This provides passive immunization for non-immune individuals exposed to varicella-zoster immunoglobulins, reducing the severity of varicella infections.
IM
Indicated for preventing and reducing the severity of chicken pox (varicella zoster virus) infections in high risk individuals within 4 days of exposure to varicella zoster virus.
NA
Concurrent use may interfere with the immune response to certain live vaccines.
History of hypersensitivity to immune globulins. IM admin should not be used in patients with severe thrombocytopenia or coagulation disorders.
Store at 2-8°C
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NA
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