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Vitamin K

Vitamin K is a group of structurally similar, fat-soluble vitamins the human body requires for complete synthesis of certain proteins that are prerequisites for blood coagulation More

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Description

Vitamin K is a group of structurally similar, fat-soluble vitamins the human body requires for complete synthesis of certain proteins that are prerequisites for blood coagulation

Generic Name

Vitamin K

Chemical names

Kinadion; Phylloquinone; Monodion; Kephton; Aqua mephyton

Brand names

NA

IUPAC name

2-methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl]-1,4-dihydronaphthalene-1,4-dione

Pharmacokinetics

NA

Actions

It is prescribed for the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phylloquinone aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of proconvertin (factor VII), active prothrombin (factor II), plasma thromboplastin component (factor IX), and Stuart factor (factor X).

Dosage/Dosage form

5-10 mg/day.

Therapeutic uses

For the treatment of haemorrhagic conditions in infants, antidote for coumarin anticoagulants in hypoprothrombinaemia.

Adverse effects/Side effects

Pain, swelling, anaphylaxis, allergic reactions.

Interaction

  • Drugs including aspirin, NSAIDs, blood thinners, anticoagulants and anti-platelet drugs may increase the effects of Vitamin K.
  • Do not consume alcohol, nicotine or tobacco while taking Vitamin K drugs.

Contraindications

Hypersensitivity

Storage

Store in a cool, dry place.

Information

Molecular weight

450.6957

Molecular formula

C31H46O2

CAS number

84-80-0

Precautions

Vitamin K formulations should be taken only under strict medical supervision. Before prescription, check clotting and bleeding time Vitamin K.