Voriconaole

Voriconazole, sold under the brand name Vfend, manufactured by Pfizer) is a triazole antifungal medication that is generally used to treat serious, invasive fungal infections.

Voriconaole

NA

NA

(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

NA

NA

NA

Prescribed for the treatment of fungal pneumonia, aspergillosis, ocular fungal infections, candidemia, fungal meningitis, pseudoallescheriosis, systemic fungal infections, cutaneous fungal infections, disseminated fungal infections, fusariosis, esophageal candidiasis, blastomycosis, coccidioidomycosis-induced meningitis, eumycetoma and invasive aspergillosis in adults and children.

NA

This interacst with warfarin, vinblastine, clopidogrel, vincristine, omeprazole, phenytoin, cyclosporine, OCPs, anti-HIV/AIDS drugs, tacrolimus, prednisolone, alfentanil, methadone, NSAIDs, tranquilizers, anti-hypertensive drugs, statins, calcium-channel blockers and oral anti-diabetic drugs.

NA

Store at 20-25°C.

Molecular weight

349.3105

Molecular formula

C16H14F3N5O

CAS number

137234-62-9

Precautions

• This is contraindicated in patients with renal diseases, hepatic disorders, electrolytic imbalances (potassium, magnesium and calcium), arrhythmia and anti-fungal drugs.
• It is contraindicated in patients with lactase deficiency or impaired lactose/galactose metabolism because this drug contains lactose.