Xylometazoline- medication which is used to improve symptoms of nasal congestion, allergic rhinitis, and sinusitis.

Xylometazoline, also spelled xylomethazoline, is a medication which is used to improve symptoms of nasal congestion, allergic rhinitis, and sinusitis.

Xylometazoline- medication which is used to improve symptoms of nasal congestion, allergic rhinitis, and sinusitis.

Xylometazoline; Xylomethazoline; Otrivine; Otriven; Otrivin

Acolate DPS, Atrovin, Biomist, Birvine, Broflex, Caxyl, Caxyl-P, Clearnoz, Cyfer, Cyfer-P, Decon, Diconal, E-Clear, Goair, Goair Kid, Hynasal-XL, Loxzol, Metalex, Mucoris Adult, Mucoris Paed, Nam Cold Nasal DPS, Nam Cold P

2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole

It is a direct acting sympathomimetic adrenergic alpha-agonist drug indicates to induce systemic vasoconstriction, thereby decreasing nasal congestion. The sympathomimetic action of this drug constricts the smaller arterioles of the nasal passages, produce a prolonged decongesting effect (8-12 hours).

0.1% solution instill into each nostril 2-3 times a day for 5-7 days.

It is used for treating nasal congestion and minor inflammation due to allergies or colds.

Headache, insomnia, tachycardia, hypertension, nervousness, dizziness, palpitation, nausea, and arrhythmia. Local burning or stinging, sneezing, dryness of mouth and throat, nausea. Eye drops: Dryness of eye.

• Hypertensive crisis with MAOIs.
• Increased heart rate or BP with sibutramine.

Angle closure glaucoma; dry rhinitis; post trans-sphenoidal hypophysectomy, trans-nasal, trans-oral surgery where dura mater is exposed.

Store below 30°C. 

Molecular weight

244.3752

Molecular formula

C16H24N2

CAS number

526-36-3

Precautions

• Pregnancy, Young children and lactation.
• Rebound congestion may occur after prolonged regular use.
• Hypertension, CV abnormalities, DM, history of excessive reaction to sympathomimetics, hyperthyroidism, difficulty in urination secondary to prostate enlargement.